The Bottom Line
PicoSure is a picosecond laser that removes tattoos significantly faster than traditional nanosecond lasers — typically requiring 4-8 sessions compared to 10-15 with older technology. It delivers ultra-short energy pulses (trillionths of a second) that shatter ink particles more completely, making it especially effective for stubborn colors like blues and greens that older lasers struggle with.
What Is PicoSure Tattoo Removal?
PicoSure is an FDA-cleared picosecond laser system specifically designed for tattoo removal. Unlike traditional Q-switched lasers that deliver energy in nanoseconds (billionths of a second), PicoSure fires pulses in picoseconds (trillionths of a second) — roughly 100 times faster. This ultra-short pulse duration creates a photoacoustic (pressure wave) effect that shatters tattoo ink into tiny particles small enough for your body's immune system to clear away.
The PicoSure uses a 755nm alexandrite wavelength as its primary beam, which is particularly effective against blue, green, and black inks — colors that are notoriously difficult for traditional lasers. This makes PicoSure a go-to option for multicolored tattoos and for patients who have had incomplete results with prior laser treatments.
Signs PicoSure May Be Right for Your Tattoo
PicoSure tattoo removal may be an especially good fit if you have blue, green, or purple ink that hasn't responded well to traditional Q-switched laser treatment, a tattoo that has shown minimal fading after multiple sessions with older laser technology ("resistant" tattoo), a desire for faster clearance with fewer total treatment sessions, a professional tattoo with dense, deep ink that requires powerful fragmentation, or lighter skin tones (Fitzpatrick types I-III) where the 755nm wavelength works most effectively.
How Does PicoSure Remove Tattoo Ink?
When the PicoSure laser fires, its ultra-short picosecond pulses penetrate the skin and are selectively absorbed by tattoo ink particles. The energy is delivered so rapidly that it creates a pressure wave (photoacoustic effect) rather than primarily heating the ink. This pressure wave shatters ink particles into fragments 10-100 times smaller than what nanosecond lasers achieve.
These tiny fragments are then engulfed by your body's macrophages (immune cells) and transported through the lymphatic system for natural elimination. Because the particles are so small, your immune system can clear them more completely and more quickly than the larger fragments produced by traditional lasers.
The selectivity of the 755nm wavelength means the laser energy is preferentially absorbed by ink particles while passing through surrounding skin tissue with minimal damage — this is the principle of selective photothermolysis that makes laser tattoo removal safe for the skin.
Treatment: What to Expect with PicoSure
Before your session: Avoid sun exposure and self-tanners for 4-6 weeks before treatment (tanned skin increases complication risk). Your provider will photograph your tattoo and may apply topical numbing cream 30-60 minutes before treatment.
During treatment: Each session takes 10-30 minutes depending on tattoo size. You'll wear protective eye shields. The laser produces a rapid snapping sensation — most patients compare it to a rubber band snapping against the skin, though some areas are more sensitive. A cooling device or cold air is often used to improve comfort.
Number of sessions: Most tattoos require 4-8 PicoSure sessions spaced 6-8 weeks apart. This compares favorably to 10-15 sessions typically needed with traditional Q-switched lasers. Amateur tattoos (less ink) may clear in 2-4 sessions, while dense professional tattoos or resistant colors may need 8-10. Complete removal is achieved in approximately 80% of tattoos.
After treatment: The treated area will appear white immediately ("frosting") — this fades within minutes. Expect redness, swelling, and possible blistering for 3-7 days. Keep the area clean, apply prescribed ointment, and avoid sun exposure. Visible fading continues for 6-8 weeks between sessions as your body clears the shattered ink.
When to See a Dermatologist
Consult a board-certified dermatologist or laser specialist for a tattoo removal consultation if you're considering removal — they can assess your ink colors, tattoo density, skin type, and recommend the most effective laser for your specific situation. During treatment, contact your provider if you notice signs of infection (increasing redness, pus, fever), blistering that doesn't resolve within 2 weeks, significant skin color changes, or scarring.
Frequently Asked Questions
How is PicoSure different from Q-switched tattoo removal?
The key difference is pulse speed. PicoSure fires in picoseconds (trillionths of a second), while Q-switched lasers fire in nanoseconds (billionths of a second). This 100x faster pulse creates more of a pressure-wave effect than a heat effect, shattering ink into much smaller particles. The result is faster clearance (4-8 sessions vs. 10-15), better results on difficult colors (blue, green), and potentially less risk of scarring due to less thermal damage to surrounding tissue.
Can PicoSure remove all tattoo colors?
PicoSure's 755nm alexandrite wavelength is excellent for black, blue, green, and purple inks. However, it is less effective on red, orange, and yellow inks, which absorb different wavelengths. For multicolored tattoos containing these warm colors, your provider may combine PicoSure with an Nd:YAG laser (1064nm/532nm) that targets red and orange pigments more effectively.
Does PicoSure tattoo removal hurt?
Most patients describe the sensation as a rapid snapping or stinging, similar to a rubber band but sharper. Pain varies by location — ribs, ankles, and spine areas tend to be more sensitive. Topical numbing cream, cold air cooling, or local anesthesia can significantly reduce discomfort. Most patients tolerate the treatment well.
Will PicoSure cause scarring?
Scarring risk with PicoSure is low — estimated at 1-3% — and lower than with older nanosecond lasers because the ultra-short pulses produce less thermal damage to surrounding skin. However, risk increases with aggressive treatment settings, treating tanned skin, or in patients prone to keloid scarring. Following your provider's post-treatment instructions carefully (especially sun avoidance) minimizes scarring risk.
References
- Brauer JA, Reddy KK, Anolik R, et al. Successful and rapid treatment of blue and green tattoo pigment with a novel picosecond laser. Arch Dermatol. 2012;148(7):820-823.
- Saedi N, Metelitsa A, Petrell K, et al. Treatment of tattoos with a picosecond alexandrite laser: a prospective trial. Arch Dermatol. 2012;148(12):1360-1363.
- Bernstein EF, Schomacker KT, Basilavecchio LD, et al. Treatment of tattoo pigment with the picosecond alexandrite laser. Lasers Surg Med. 2017;49(7):652-659.
Trusted Resources
- American Academy of Dermatology Association. "Tattoo Removal." aad.org
- American Society for Dermatologic Surgery. "Laser Tattoo Removal." asds.net
- FDA. "Tattoo Removal: Know the Risks." fda.gov
Always choose a board-certified dermatologist or laser specialist with specific experience in tattoo removal for the safest, most effective results.